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Tracking Indian made vaccine found on terrorists who attacked Karachi Airport

brother...is it a vaccine or an anti coagulating agent...I am waiting for reliable sources everything we know is based on media's jumping to conclusion habit
Lots of medicines have multiple uses. Sometimes intended, sometimes discovered by accident. The most famous present day example being Viagra that was a result of Pfizer's attempt to create a drug for high blood pressure.

Similarly, this vaccine normally intended for use in cancer situations also seems to be an effective blood clotter (going by what is being repeated in Pakistani media)
 
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I didnt say the factor 8 does...I said the coagulating does as it is the 1st step (layman speaking) to an open wound


brother...is it a vaccine or an anti coagulating agent...I am waiting for reliable sources everything we know is based on media's jumping to conclusion habit
I am also confused in this case.Duffer media with unprofessional attitude :angry:
 
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I didnt say the factor 8 does...I said the coagulating does as it is the 1st step (layman speaking) to an open wound


brother...is it a vaccine or an anti coagulating agent...I am waiting for reliable sources everything we know is based on media's jumping to conclusion habit

It can't be vaccine - vaccine contains pathogen (attenuated or dead or toxoid) designed to elicit an immunologic response hence attaining active immunity. Neither it can be anticoagulant, for anticoagulant prevents coagulation of the blood. Injecting anticoagulant would mean preventing blood from coagulation - in simple words being remain prone to bleed again and again.

If terrorists were carrying something then it must got to be an agent that helps blood to coagulate (pro coagulant) or help wound to stop bleed as quickly as possible.
 
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It can't be vaccine - vaccine contains pathogen (attenuated or dead or toxoid) designed to elicit an immunologic response hence attaining active immunity. Neither it can be anticoagulant, for anticoagulant prevents coagulation of the blood. Injecting anticoagulant would mean preventing blood from coagulation - in simple words being remain prone to bleed again and again.

If terrorists were carrying something then it must got to be an agent that helps blood to coagulate (pro coagulant) or help wound to stop bleed as quickly as possible.
oh sorry pro coagulant...sorry am trying to kill 3 birds with 1 stone, reading a molecular bio article, drinking steaming hot chocolate while replying....
 
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@Emmie
sir,thnks for clearing that up,,,,,,,actually havent been in touch with patho/physio of late,,,,,,,
currently taking coaching classes,which i hope will help me get through all india pg exams,,,next up is obsgynae,,which i dislike more thn spm.....:sick:
frank,breach,pelvic diametrs,mole pregncy,ca stagings,,,,the horror:cry::cry:
 
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Hon you reap what you sow!!!
Right now this idiom suits you and your country.
We are reaping what our elected shit sowed (basically ignored) but Indian being bitches was not part of it :disagree:
 
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What a load of crap............ ISI is good at ONLY one thing........ uncovering "Indian hand" in all of their misadventures! :D
 
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Lots of medicines have multiple uses. Sometimes intended, sometimes discovered by accident. The most famous present day example being Viagra that was a result of Pfizer's attempt to create a drug for high blood pressure.

Similarly, this vaccine normally intended for use in cancer situations also seems to be an effective blood clotter (going by what is being repeated in Pakistani media)
Dude the drugs oncodox or whatever is a chemotherapeutic drug which hinders replication while blood clotting has nothing to do with replication...One (esp if that person is learned in that field) needs to know when to let go and what media source to pick! Apparently you know neither!
 
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I have made the above post after research,first of all...second I myself am biology student..so who could understand chemicals and their effects on various biological processes more then us?
I dont know that what kind of discussion is going on here as I haven't seen 10 page long debate...but I am seeing that a sort if misunderstanding is observed among people here.
Keeping all the siyasi conversation away.. Let me again elucidate that Factor 8 is an essential protein found in our body.It's deficiency causes haemophelia.
When we are injured.. this protein triggers a series of reactions as a result of it's stimulus ..a series of reaction is initiated to clot and heal our wounds.
Now what it has to do with cancer and hemophilia? well this medicine is used to stop bleeding
IIt doesn't triggers coagulation, it's also emetegenic, the side effects are a lot for any anti-cancerous drugs, i wonder after injecting this they would be able to keep a cool head.

All chemotherapy agents, produce nausea, vomiting,headaches etc.There is no way around this.

Doxorubicin drug information | DrugsUpdate India

Do you know what you write? it contains Doxorubicin

Doxorubicin trade name Adriamycin; also known as hydroxydaunorubicin) is a drug used in cancer chemotherapy. It is an anthracycline antibiotic, closely related to the natural product daunomycin, and like all anthracyclines it intercalates DNA. It is commonly used in the treatment of a wide range of cancers, including hematological malignancies, many types of carcinoma, and soft tissue sarcomas.
The drug is administered in the form of hydrochloride salt intravenously. It may be sold under the brand names Adriamycin PFS, Adriamycin RDF, or Rubex.It is photosensitive and it is often covered by an aluminum bag to prevent light from affecting it.

Pharmacokinetics
Doxorubicin is a cytotoxic anthracycline antibiotic. The cytotoxic action results from its binding to DNA and inhibition of nucleic acid synthesis. Doxorubicin has been shown to produce regression in a variety of disseminated malignancies.
Absorption: Rapidly cleared from the blood after IV admin.
Distribution: Distributed into tissues including lungs, liver, heart, spleen and kidneys (IV); crosses the placenta; enters breast milk.
Metabolism: Hepatic; rapidly converted to doxorubicinol.
Excretion: Bile (as unchanged drug); 12 min, 3.3 hr, 30 hr (mean elimination half-lives).

Doxorubicin Adverse Reactions / Doxorubicin Side Effects
Leucopenia, thrombocytopenia, nausea, vomiting, diarrhoea. Rarely facial flushing, rash, alopecia. Blurred vision, headache, seizures, paraesthesia, confusion, malaise, lethargy, skin pigmentation.
Potentially Fatal: Bone marrow suppression, cardiotoxicity.

Precautions
General
Doxorubicin is not an anti-microbial agent. Doxorubicin is emetigenic. Antiemetics may reduce nausea and vomiting; prophylactic use of antiemetics should be considered before administration of Doxorubicin, particularly when given in conjunction with other emetigenic drugs.

Overdosage:
Acute overdosage may increase the toxic effects of mucositis, leukopenia and thrombocytopenia. Treatment includes hospitalisation of the severely myelosuppressed patient, antimicrobials, platelet transfusions and symptomatic treatment of mucositis. Use of haemopoietic growth factor (G-CSF, GM-CSF) may be considered. Cumulative dosage increases risk of cardiomyopathy and resultant congestive heart failure which may be managed with digitalis preparations, diuretics, and after load reducers such as ACE inhibitors.

Special Precautions
Elderly, children, hepatic impairment. Monitor blood counts and ECG.

Other Drug Interactions
Doxorubicin interacts with a number of other drugs e.g. antibiotics (aminoglycosides), steroids, aminophylline and propranolol.
Potentially Fatal: Cholestasis induced by mercaptopurine may be potentiated by concurrent administration of the drug. Toxicity may be increased if streptozocin is given concurrently.

Dosage
Intravenous
AIDS-related Kaposi's sarcoma
Adult: As pegylated liposome: 20 mg/m2 BSA infused over 30 min once every 2-3 wk.
Hepatic impairment: Moderate impairment (serum-bilirubin: 12-30 mcg/mL): Half the normal dose; severe impairment (serum-bilirubin >30 mcg/mL): Quarter of the usual dose.
Intravenous
Ovarian carcinoma
Adult: As pegylated liposome: 50 mg/m2 BSA infused over 1 hr once every 4 wk.
Hepatic impairment: Moderate impairment (serum-bilirubin: 12-30 mcg/mL): Half the normal dose; severe impairment (serum-bilirubin >30 mcg/mL): Quarter of the usual dose.
Intravenous
Metastatic breast cancer
Adult: 60-75 mg/m2 BSA once every 3 wk in combination with cyclophosphamide given as an infusion over 1 hr diluted in 0.9% sodium chloride or 5% glucose.
Hepatic impairment: Moderate impairment (serum-bilirubin: 12-30 mcg/mL): Half the normal dose; severe impairment (serum-bilirubin >30 mcg/mL): Quarter of the usual dose. Irrigation
Local malignant neoplasms in the bladder
Adult: 50 ml of a 1 mg/ml solution instilled into the bladder for 1 hr once a mth.
Hepatic impairment: Moderate impairment (serum-bilirubin: 12-30 mcg/mL): Half the normal dose; severe impairment (serum-bilirubin >30 mcg/mL): Quarter of the usual dose.
 
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It triggers coagulation, but not as suggested as a quick fix on battlefield.it might reduce bleeding and clotting time but it's also emetegenic, the side effects are a lot for any anti-cancerous drugs, i wonder after injecting this they would be able to keep a cool head.

All chemotherapy agents, produce nausea, vomiting,headaches etc.There is no way around this.

This anthracycline antibiotic intercalates the DNA which directly affects the transcription and replication of DNA.

Doxorubicin is used to treat different types of cancers that affect the breast, bladder, ovary, thyroid, stomach, lungs, bones, nerve tissues, muscles, joints, and soft tissues. Mechanism : Chemotherapy primarily refers to the treatment of cancer with an antineoplastic drug or with a combination of such drugs into a standardized treatment regimen. Certain chemotherapy agents also have a role in the treatment of other conditions, including ankylosing spondylitis, multiple sclerosis, Crohn's disease, psoriasis, psoriatic arthritis, rheumatoid arthritis and scleroderma. Usage : cancer. Side Effects : Cardiotoxicity, alopecia, cardiomyopathy, stomatitis, stomach upset, skin rash, acute toxicity.

Nowhere does it say it can be used to trigger coagulation...its 2 separate stories...get your facts right please!
 
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This anthracycline antibiotic intercalates the DNA which directly affects the transcription and replication of DNA.

Doxorubicin is used to treat different types of cancers that affect the breast, bladder, ovary, thyroid, stomach, lungs, bones, nerve tissues, muscles, joints, and soft tissues. Mechanism : Chemotherapy primarily refers to the treatment of cancer with an antineoplastic drug or with a combination of such drugs into a standardized treatment regimen. Certain chemotherapy agents also have a role in the treatment of other conditions, including ankylosing spondylitis, multiple sclerosis, Crohn's disease, psoriasis, psoriatic arthritis, rheumatoid arthritis and scleroderma. Usage : cancer. Side Effects : Cardiotoxicity, alopecia, cardiomyopathy, stomatitis, stomach upset, skin rash, acute toxicity.

Nowhere does it say it can be used to trigger coagulation...its 2 separate stories...get your facts right please!

I was saying the same thing, where is it mentioned it helps coagulation? it was mentioned by @Slav Defence , i was merely saying it is a cancer drug not clotting factor.
 
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It triggers coagulation, but not as suggested as a quick fix on battlefield.it might reduce bleeding and clotting time but it's also emetegenic, the side effects are a lot for any anti-cancerous drugs,
You tell me :pop:

Factor 8 is a different thing and oncodox is a different thing altogether...
 
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Whats the crux of this whole thread? Who made the doo doo ... Indian intel agencies or Pak media !!
 
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