Dont you think its not going to be disruptive in medical world?
2013-07-10 11:12
Zhongshan Hospital, Fudan University
China made biodegradable cardiovascular stents will enter clinical trials
Chinese Academy of Sciences, Zhongshan Hospital, Fudan University, director of Cardiology Junbo Ge, a few days ago in Paris, France Euro-PCR Conference "Innovative stents and Platform" at the venue made a presentation entitled "The new generation is completely biodegradable stent platforms: Xinsorb bracket," the special report .
It is the Chinese self-developed fully biodegradable stents (Xinsorb) for the first time at the international conference announced. Currently, the holder has passed the approval of the Ethics Committee, will conduct clinical trials in Zhongshan Hospital.
According to reports,
is completely biodegradable stent coronary intervention called "fourth revolution" is expected over the next decade will likely dominant coronary stent market. Currently, only a handful of multinational companies internationally to grasp the stent technology.
Following developed the world's first biodegradable stent coating after Junbo Ge team after three years of research, with the relevant enterprises, successfully developed a new generation of localization is completely biodegradable stents "Xinsorb". The bracket is constructed of polylactic acid polymer drug delivery platform, implanted in the body 2 to 3 years is completely degraded and absorbed.
Unlike conventional metal stents, the design philosophy is: after stent implantation in a period of time, the narrowed blood vessels to mechanical support, while the release of the drug to prevent restenosis after stent that is slowly degraded and completely organized absorption, vascular structures, and systolic and diastolic function fully restored to a natural state.
Xinsorb bracket preclinical animal research data showed that the supporting force and metal stents (Firebird2) similar. Quantitative analysis of coronary angiography and optical coherence tomography follow-up six months confirmed that its ability to suppress intimal proliferation and Firebird2 similar, and in endothelial and inflammatory reactions of metal stents with no significant difference. Participate in Euro-PCR meeting of international experts fully affirmed the stent preclinical findings, and China's homegrown completely biodegradable stents expressed great concern.
It is understood, Euro-PCR conferences in Europe and the world's most influential annual meeting interventional cardiology, cardiovascular intervention has championed innovative technology dissemination and promotion. Fully biodegradable stent clinical and basic research, is one of the hotspots this year's conference.
Junbo Ge said at the meeting, the localization is completely biodegradable stents will accelerate the development of cardiovascular medical devices, our pace of innovation.
Subsequently, the research team will continue to develop and optimize the design and performance of the stent, and will focus on "Cardiovascular stent system research", "structural heart disease, interventional techniques and equipment research," "renal sympathetic nerve ablation technology and equipment research "and other three directions involved in translational medical research, the formation of a core technology of high levels of cardiovascular medical products research and development capabilities, and strive to promote and push our own intellectual property research and development of new cardiovascular interventional devices.
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