The Mi-171Sh is armed with a Shturm-V high-precision guided missile system. The missiles can destroy modern battle tanks protected by explosive reactive armour, fortified points and aerial targets. The Shturm-V missile complex launches Ataka supersonic missiles equipped with a hollow-charge warhead for defeating armoured targets. The missile can destroy aerial targets with a fragmentation warhead and lightly armoured combat materiel by using a high-explosive warhead.
The Mi-171Sh is also provided with hardpoints to carry up to 80 S-8 unguided rockets and GSh-23L 23mm cannons, with an ammunition load of 500 rounds.
Small arms, such as the 7.62mm PKT machine gun, PK machine gun and RPK light machine gun, are mounted in the nose and rear fuselage sections. The gun pivots provided at the doorway and near the windows allow the onboard troops to operate these weapons during flight.