Pakistani scientist discovers disease caused by interfamily marriage.

[Verve]

Because they are double faced hypocrites

yeah that they are.

Waiting for one of them to suggest making gene screening mandatory prior to marriage ...

 

[313ghazi]

[



"Its missing all scientific facts".
OK so this ladies years worth of international research vs your oversimplified explanation.

You said it yourself. Relatives have a similar genotype. They both could be silent carriers of a genetic disease. When you're indulging in cousin marriage youre increasing the chances of your offspring having a a recessive genotype exponentially (be reminded that there's not one but hundreds of genetic diseases that occur due to recessive alleles). Why would you be part of something that's known to give off retarded children ?


The Rothschild and British royal family being inbred holds as much weight as the earth being flat. We're seeing it ourselves nowadays that both british princes have married pretty far away from their families. I'm not 100% sure about other royal families but it'd make no sense to keep inbreeding now that most of the world is run by democracies and not monarchies.

You completely missed my point. The science is spot on. The article is poorly written, lacks any scientific content and turns the focus from genetics to a social/political issue.

Nobody in this topic has discussed the science or congratulated the scientist on the breakthrough, instead we are all discussing cousins.

 

[Maarkhoor]

Scientist should work on British or Ex Pakistani parents kids who wants to be white Britis but never let a chance to defame their own parents motherland. Trying hard to prove that cousin marriage produce retard kids despite their own parents are first cousins.

 

[RowdyRathore]

Siddiqui Syndrome LOL Everybody knows the side effects of inter family marriages since 1000s BC.

 

[TheLahoriGuy]

Because they are double faced hypocrites... in one post they will be mocking the intra-family marriages but in the other they will rant against the ummah ....

How are the two even related ? Unless you're claiming the ummah is inbred.

Desi suculars and liberals go berserk at the suggestion of cross ethnicity breeding etc especially with migrants ... noticed that?

The liberals are the one that go berserk at the suggestion of cross ethnicity breeding ? Well at least you have a sense of humor.

Liberals are the ones discouraging this act. Is it the liberals that sh*t themselves when they see a Muslim marrying a Jew or Christian ? The entire concept of being a liberal is being open-minded and resistant to norms. Are you sure you even know what a liberal is ?

 

[Ocean]

Lmao what is more funny is that on this forum a new trend is emerging amongst indian hindus and pseduo pak liberals that anyone who counters their "cousin marriage causes abnormality argument", they automatically assume those posters have married their cousins or were born to cousin parents and start abusing them with "oh you are a product of cousin marriage" insults hence you have low intellect. Lmao

Report him, he is a false flagger

Islam discourages intra-family marriages.

If one has the need to drag in islam then they should find out exact sources to back their claim. Some weeks back i think waz had made some comment , i had asked him for sources , which he provided and there was not a single narration from prophet that discouraged cousin marriages. All his sources were weak, there was one reference towards hazrat Umar who had passed on a family that suffered from some disease and rest of narrations were extremely weak that one cant even use them as an argument.

Here Paksword post already mentions it

Although cousin marriage is allowed in Islam, there are some weak narrations (extremely weak) discouraging it..

“Marry outside the family, lest the offspring be thin and weak.” [Ibn Hajar, Talkhis al-Habir]

But Hazrat Umar has suggested to marry outside of the family/ tribe, when he saw the people of that tribe become very weak..

“You all have become thin and weak, so marry outside the family.” [Iraqi, Takhrij Ahadith al-Ihya’]

Hanbali fiqh explicitly mentions that it is recommended (mustahabb) for a man to marry outside the family, as doing so normally leads to healthier and stronger offspring.

Cousin-banging families must not be provided with medical facilities in case of genetic diseases or even some systemic diseases (since they have higher genetic predisposition). Why should the state be burdened for their stupid family politics/economics leading to such marriages.

Cousin-bangers would cite some religious injunctions and cultural pride while everybody knows that cousin marriages are arranged to keep the wealth within the family. So much for their false pride

As long as they are not banging ur family women why should it bother you. And pakistani gov hospitals dont offer much treatment to kids with special needs, majority of these kids parents get them treated at private clincis because our health system is so broken.

Every time when this debate rages.. some cousin fucker here comes and tells how 999999 members of his family are inbred and still okay!!

this is not empirical behaviour but just defending bullshit for the sake of it

Yeah they should follow hindu system of marrying single woman to 5-6 brothers at a time or keeping devadasis at the temples who produce offsprings for every priest who bangs them

Islamabad - A scientist at Institute of Biomedical and Genetic Engineering (IBGE), in collaboration with researchers of Europe and Singapore, has discovered a new disease in Pakistan that leads to the lifetime paralysis of the patient. The cause of the disease is interfamily marriage .

The disease coined as ‘siddiqi syndrome’ causes deafness in the patient at the age of six months and leads to a complete paralysis of the body by the age of eleven. This ‘deafness-dsytonia’ includes repetitive muscle contractions their twisting and other abnormal movements.

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Dr. Saima Siddiqi of IBGE researched for eight years on a family in Pakistan in which this rare disease was found. Among the nine children of the family, five suffer from this disease . The children named Shabana, Nosheen, Adnan, Rehman and Abdullah, are of different ages. She found the family through Edhi center.

“Initially, the disorder was ignorantly reported as caused by ‘supernatural powers’ or ‘black magic’, but research unveiled that the disease was borne due to interfamily marriage ,” said Dr. Saima.

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Interfamily marriages have given a unique texture to genetic landscape of Pakistan due to which diseases considered rare around the globe are found in Pakistan. A unique event at DNA level commonly known as a mutation may result in any rare diseases.

During research, patients were examined in National Hospital Singapore (NHS) to determine the clear idea of phenotype. Modern research techniques including Whole Genome SNP analysis and Next Generation Sequencing (NGS) helped researchers to identify a lethal change in the genetic code in a gene named as FITM2.

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The researchers observed that the change in genetic code stopped the function of a gene that was involved in fat metabolism and energy production.

Further, experiments of fruit flies and mouse modeling produced similar results on patients thus confirming the involvement of FITM2 gene in development of the disease in patients.

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Dr. Siddiqi, who is currently researching on 200 other families, said that the ratio of this disease in Pakistan would be high because of the social structure of the society.

She said that a few healthy generations in a family do not guarantee the non-transferring of the syndrome to the upcoming generation.

Dr. Siddiqi said that the expectancy rate of the disease is high in less educated and poor families.

“Lack of awareness is one of the major reasons for transferring of this disease to the next generation,” she said.

According to her, such families must be educated and encouraged for arranging the marriages of at-least one generation out of the family to reduce the chances of disease .

She added that the life expectancy and recovery from the syndrome could not yet be determined, but could be avoided by conducting premarital blood screening of the individuals before marriage .

She said that the detection of this disease reflects that the genetic evaluation process has been halted in the families, and to erase such deficiencies maximum marriages must be carried out of the family.

However, she added, the lack of facilities for the pre-marital blood screening and research on rare diseases is also an obstacle to counter the flourishing of such syndrome.

“Public hospitals do not provide the facility of premarital blood screening and the government must do something about it,” she said.

Dr. Siddiqi lamented that the government prefers to research on common diseases as compare to the rare ones.

Director IBGE, Dr. Muhammad Ismail said that there is a need of genetic counseling in the public sector hospitals to edcuate large numbers of people on such diseases.

“Cousin Marriages also need to be discouraged as it leads to the pool of defective generations,” he added.

Dr Siddiqi added, “Now this family knows that they have genetic disease running in their family and that they need carrier screening for couples. Although this diagnosis has deprived them of the hope that they can be treated immediately, it’s the start of new hope for them that one day they will have a definite treatment.”

Lmao do you know how viruses, diseases disorders and syndromes' identification works , and how diseases are officially classified under categories ? Any scientist could come up with a claim ; whether right or wrong, that i have discovered this and that virus or disorder, but unless his work is peer reviewed , tested and verified by other scientists and published in international scientific journal, no such research is considered to hold water.

Also no claim by any scientist is bought unless he or she publishes entire scientific paper detailing that disease. In medical world single line explanations like ones provided in OP don't work.

The mere fact you tried to use a news report with no medical standing ,with no scientific papers link provided (by the "geneticist" ) to back the reserach findings, with no other required credentials added to verify the research as authentic , just shows your iq is in dumps.

 

[PakSword]

I have a question....

if a family/ tribe people have mostly strong genes.. their height is over 6.5 feet, bones and muscles are strong, no history of cancer and any other disease, life expectancy is over 100 years.. should they marry in weaker families, who have history of different illnesses etc?

Of course, that weaker tribe will get a lot of benefit of the gene pool sharing, but the strong and healthy tribe's next generation will carry and pass on some weak genes to the next generations..

 

[YeBeWarned]

Don't they have better name for that Syndrome ? my last name is Siddiqui

 

[TheLahoriGuy]

Don't they have better name for that Syndrome ? my last name is Siddiqui

Hahaha perfect example of making a scientific discovery backfiring

 

[Divergent]

Scientist should work on British or Ex Pakistani parents kids who wants to be white Britis but never let a chance to defame their own parents motherland. Trying hard to prove that cousin marriage produce retard kids despite their own parents are first cousins.

But sweet some of our parents are non-related and produce pretty fine kids MA

 

[Maarkhoor]

But sweet some of our parents are non-related and produce pretty fine kids MA

Choor ki dardi mien tinkaa?.

 

[Ocean]

I have a question....

if a family/ tribe people have mostly strong genes.. their height is over 6.5 feet, bones and muscles are strong, no history of cancer and any other disease, life expectancy is over 100 years.. should they marry in weaker families, who have history of different illnesses etc?

Of course, that weaker tribe will get a lot of benefit of the gene pool sharing, but the strong and healthy tribe's next generation will carry and pass on some weak genes to the next generations..

Yes happens like one of my uncles family has tall heights but in his wifes family men and women are not tall,though they are healthy and strong but not very heighted, so uncle's son's height has turned out to be avg though i expected he will be as tall as his dad.

Also if you marry into a family which has genetic diseases like diabetes, arthritis etc then you can expect them to show up in your offspring even if you have zero family history of it.

Lets make some new genetic discovery and without publishing a scientific paper lets get it published in some local newspaper. We will name it as "Khaala Parveen syndrome" ,if she could name it siddiqui syndrome without consulting with ANY OTHER geneticist or scientist.

 

[Lavrentiy]

As long as they are not banging ur family women why should it bother you.

I don't give a damn about the ethical issues (if any) regarding cousin marriages. My concern is only the socio-economic burden on such families and the society. Additionally, I consider such diseased children as unfortunate victims.

I am all fine with cousin banging if contraceptives are being used. Carry on please

 

[Divergent]

Choor ki dardi mien tinkaa?.

What language are you talking

 

[war&peace]

If one has the need to drag in islam then they should find out exact sources to back their claim. Some weeks back i think waz had made some comment , i had asked him for sources , which he provided and there was not a single narration from prophet that discouraged cousin marriages. All his sources were weak, there was one reference towards hazrat Umar who had passed on a family that suffered from some disease and rest of narrations were extremely weak that one cant even use them as an argument.

That's I didn't say it is haram or forbidden but only discouraged...not even condemned. And for that you don't need strong explicit references as required when declaring halal or haram. If you look at the ethos of Islam and the concept of pan-Islamism which encourages stronger bonds between the Muslims of different backgrounds and ethnicities etc, you will realise the marriage outside the family are encouraged. I can provide you references too since I worked on it some time ago... but right now I have to go with my family...

What language are you talking

Punjabi I guess