You can never challenge US supremacy when you align Asian and East European country and start challenging the US in Asia. US in asia is not that big of an influence. Just look at how many country in Asia is US camp vs how many not, and you'll see
At best US will lose interest in Asia, that does not mean the end of the United States Dominance. At best you will see US lose a hand to save an Arm.
You can only challenge US Supremacy on US Soil, when the power is at its greatest, to have that to work, China or India need to form an alliance with Canada or Mexico, then we can talk. Otherwise you can destroy the US with that pact (But in turn all youse will be destroyed too by MAD) You cannot challenge US supremacy far away in Asia. There are no hope to that