Want a response? Test a Satellite Launch Vehicle or ICBM. That's the response. Summon the ambassador and voice your displeasure and evict the local intelligence officers the embassy. Close all borders into and out of Afghanistan, including NATO supplies.
But the response will instead be "don't blame us, your policy isn't working, we killed all of our terrorists". The response will be ignored and the status quo will likely continue, gradually deteriorating relations until, not only will Pakistan not receive aid or reimbursement of expenses. (which would actually be better for Pakistan), but proxy wars will increase and you will see more violence in Pakistani streets and eventual sanctions after a false flag operation in India or Afghanistan.