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ELION, GERTRUDE
Gertrude Belle Elion (January 23, 1918 - February 21, 1999) was a Nobel Prize winning biochemist who invented many life-saving drugs, including 6-mercaptopurine (Purinethol) and 6-thioguanine (which fight leukemia), Imuran, Zovirax, and many others. Elion worked at Burroughs-Wellcome (now called Glaxo Wellcome) for decades (beginning in 1944) with George Hitchings and Sir James Black, with whom she shared the Nobel Prize. She is named on 45 patents for drugs and her work has saved the lives of thousands of people.
GOODE, SARAH S.
Sarah E. Goode was a businesswoman and inventor. Goode invented the folding cabinet bed, a space-saver that folded up against the wall into a cabinet. When folded up, it could be used as a desk, complete with compartments for stationery and writing supplies. Goode owned a furniture store in Chicago, Illinois, and invented the bed for people living in small apartments. Goode's patent was the first one obtained by an African-American woman inventor (patent #322,177, approved on July 14, 1885).
HYDE, IDA HENRIETTA
Ida Henrietta Hyde (1857-1945) was an American physiologist who invented the microelectrode in the 1930's. The microelectrode is a small device that electrically (or chemically) stimulates a living cell and records the electrical activity within that cell. Hyde was the first woman to graduate from the University of Heidelberg, to do research at the Harvard Medical School and to be elected to the American Physiological Society.
KARLE, ISABELLA L.
Isabella Helen Lugoski Karle (1921- ) is a American physical chemist who invented new methods of X-ray Crystallography. She used electron diffraction and then x-ray diffraction to study the structure of molecules. Karle developed a three-dimensional modeling process, enabling her to identify and show the structures of hundreds of complex and important molecules (including alkaloids, ionophores, steroids, toxins, and peptides [amino acid compounds]). Because of Karle's process, the number of published molecular analyses has jumped from about 150 to over 10,000 per year. Karle received the National Medal of Science in 1995. Karle is a senior scientist and head of the Naval Research Laboratory's (NRL) x-ray diffraction section in the Laboratory for the Structure of Matter. Karle's husband, Jerome Karle, is a Nobel Prize winner in chemistry.
YALOW, ROSALYN S.
Dr. Solomon A. Berson (1919-1972) and Dr. Rosalyn Sussman Yalow (1921- ) co-invented the radioimmunoassay (RIA) in 1959. The radioimmunoassay is a method of chemically analyzing human blood and tissue and is used diagnose illness (like diabetes). RIA revolutionized diagnoses because it uses only a tiny sample of blood or tissue and is a relatively inexpensive and simple test to perform. Blood banks use RIA to screen blood; RIA is used to detect drug use, high blood pressure, infertility, and many other conditions and diseases. For inventing RIA, Yalow won the Nobel Prize in Medicine in 1977 (Yalow accepted for Berson, who died in 1972). Yalow and Berson did not patent the RIA; instead they allowed the common use of RIA to benefit human health.
WU, CHIEN-SHIUNG
Dr. Chien-Shiung Wu (Shanghai, China, May 31, 1912 - New York, USA, February 16, 1997) was a nuclear physicist who studied beta-decay (a weak interaction in which one of the neutrons in the nucleus of an atom decays into a proton and an electron; the proton enters the nucleus, forming an isotope, and the electron is emitted as a beta-particle). In 1956, Madam Wu did experiments showing that parity is not conserved in weak interactions (demonstrating parity violation in the nuclear beta decay in cobalt 60). Her experiments supported T. D. Lee and C. N. Yang's revolutionary idea that parity was not conserved in weak interactions (parity conservation had been a basic assumption in physics). Madam Wu worked on the Manhattan Project (a secret US project during World War 2 to develop an atomic bomb in order to defeat Hitler), developing a process for separating the uranium isotopes U235 and U238 by gaseous diffusion. She also helped develop more sensitive Geiger counters (devices that detect radiation). Madam Wu also studied the molecular changes in hemoglobin associated with sickle-cell anemia.
Alice H. Parker
(Morristown, NJ)
Issued a patent in December 19,1919 for a heating furnace. The invention provided a mechanism for regulating heat to be carried to vaious rooms of a building.
Marie V.Brittan Brown
In Dec.2,1969 Home security system
Ruane Sharon Jeter
(Los Angeles, CA)
In Apr 14,1987 Toaster
Gertrude Belle Elion (January 23, 1918 - February 21, 1999) was a Nobel Prize winning biochemist who invented many life-saving drugs, including 6-mercaptopurine (Purinethol) and 6-thioguanine (which fight leukemia), Imuran, Zovirax, and many others. Elion worked at Burroughs-Wellcome (now called Glaxo Wellcome) for decades (beginning in 1944) with George Hitchings and Sir James Black, with whom she shared the Nobel Prize. She is named on 45 patents for drugs and her work has saved the lives of thousands of people.
GOODE, SARAH S.
Sarah E. Goode was a businesswoman and inventor. Goode invented the folding cabinet bed, a space-saver that folded up against the wall into a cabinet. When folded up, it could be used as a desk, complete with compartments for stationery and writing supplies. Goode owned a furniture store in Chicago, Illinois, and invented the bed for people living in small apartments. Goode's patent was the first one obtained by an African-American woman inventor (patent #322,177, approved on July 14, 1885).
HYDE, IDA HENRIETTA
Ida Henrietta Hyde (1857-1945) was an American physiologist who invented the microelectrode in the 1930's. The microelectrode is a small device that electrically (or chemically) stimulates a living cell and records the electrical activity within that cell. Hyde was the first woman to graduate from the University of Heidelberg, to do research at the Harvard Medical School and to be elected to the American Physiological Society.
KARLE, ISABELLA L.
Isabella Helen Lugoski Karle (1921- ) is a American physical chemist who invented new methods of X-ray Crystallography. She used electron diffraction and then x-ray diffraction to study the structure of molecules. Karle developed a three-dimensional modeling process, enabling her to identify and show the structures of hundreds of complex and important molecules (including alkaloids, ionophores, steroids, toxins, and peptides [amino acid compounds]). Because of Karle's process, the number of published molecular analyses has jumped from about 150 to over 10,000 per year. Karle received the National Medal of Science in 1995. Karle is a senior scientist and head of the Naval Research Laboratory's (NRL) x-ray diffraction section in the Laboratory for the Structure of Matter. Karle's husband, Jerome Karle, is a Nobel Prize winner in chemistry.
YALOW, ROSALYN S.
Dr. Solomon A. Berson (1919-1972) and Dr. Rosalyn Sussman Yalow (1921- ) co-invented the radioimmunoassay (RIA) in 1959. The radioimmunoassay is a method of chemically analyzing human blood and tissue and is used diagnose illness (like diabetes). RIA revolutionized diagnoses because it uses only a tiny sample of blood or tissue and is a relatively inexpensive and simple test to perform. Blood banks use RIA to screen blood; RIA is used to detect drug use, high blood pressure, infertility, and many other conditions and diseases. For inventing RIA, Yalow won the Nobel Prize in Medicine in 1977 (Yalow accepted for Berson, who died in 1972). Yalow and Berson did not patent the RIA; instead they allowed the common use of RIA to benefit human health.
WU, CHIEN-SHIUNG
Dr. Chien-Shiung Wu (Shanghai, China, May 31, 1912 - New York, USA, February 16, 1997) was a nuclear physicist who studied beta-decay (a weak interaction in which one of the neutrons in the nucleus of an atom decays into a proton and an electron; the proton enters the nucleus, forming an isotope, and the electron is emitted as a beta-particle). In 1956, Madam Wu did experiments showing that parity is not conserved in weak interactions (demonstrating parity violation in the nuclear beta decay in cobalt 60). Her experiments supported T. D. Lee and C. N. Yang's revolutionary idea that parity was not conserved in weak interactions (parity conservation had been a basic assumption in physics). Madam Wu worked on the Manhattan Project (a secret US project during World War 2 to develop an atomic bomb in order to defeat Hitler), developing a process for separating the uranium isotopes U235 and U238 by gaseous diffusion. She also helped develop more sensitive Geiger counters (devices that detect radiation). Madam Wu also studied the molecular changes in hemoglobin associated with sickle-cell anemia.
Alice H. Parker
(Morristown, NJ)
Issued a patent in December 19,1919 for a heating furnace. The invention provided a mechanism for regulating heat to be carried to vaious rooms of a building.
Marie V.Brittan Brown
In Dec.2,1969 Home security system
Ruane Sharon Jeter
(Los Angeles, CA)
In Apr 14,1987 Toaster
