Indian scientists discover insulin pills for diabetics

[HariPrasad]

One more contribution of Indian to humanity in recent time. Congrats to all fellow Indians.

 

[Rajput_Pakistani]

Go and tell it to American Chemical Society Journal.

Also, look at the way diabetes pills work.

Re-read the article and if you still don't understand it, burst the bubble again, and I will splash your brain in layman's terms.

Hahahahah

Ok go ahead first tell me what is first Pass effect?
What is "parenteral", "Oral"?
What is the difference between "Capsule", "Pill" and Tablet?
What is "Film Coated"?
What are the "Enzymes"?
Why Insulin cant be taken orally?

Tell me everything then i will burst your "Cheecho" Indian brain once and for all

 

[Chronos]

@KRAIT ...You are fast man, I was going to post this..

Beat him up for stealing your glory

 

[Spring Onion]

God Bless you if you have succeeded to treat the ailment through an easier medication.

 

[liall]

Did they already made the pill or is it that they could be made? I have read similar articles in the past.

 

[SpArK]

Scientists report new development toward long-sought insulin pill for diabetes treatment

Insulin Pill Is Breakthrough In Diabetes Treatment, Provides New Way For Body To Lower Blood Glucose

 

[kbd-raaf]

Hahahahah

Ok go ahead first tell me what is first Pass effect?
What is "parenteral", "Oral"?
What is the difference between "Capsule", "Pill" and Tablet?
What is "Film Coated"?
What are the "Enzymes"?
Why Insulin cant be taken orally?

Tell me everything then i will burst your "Cheecho" Indian brain once and for all

Buddy, I could Google all of those questions, you've proved nothing.

 

[Rajput_Pakistani]

Buddy, I could Google all of those questions, you've proved nothing.

Buddy you can google all you want. I am only telling you and OP that this discovery has already been made and commercial oral insulin is available in market. Its you who have to prove that it is the discovery of an Indian scientist not me. Thanks

 

[KRAIT]

@Rajput_Pakistani

Objective of Research ---- A way to transform delivery of insulin therapy

Challenge ---- From a shot to a pill. (Direct Delivery of Insulin)

Introduction

1. The body's digestive enzymes. ----
Extremely efficient in breaking down food.
It also break down insulin before it can get to work.

2. Insulin doesn't get easily absorbed through the gut into the bloodstream.

For Delivery Mechanism-

1. Packaging insulin in tiny sacs made of lipids, or fats called liposomes,(lready used in some treatments.)
2. Then, they wrapped the liposomes in layers of protective molecules called polyelectrolytes.

For Better Absorption into Bloodstream -
Folic acid, a kind of vitamin B ( helps in transporting liposomes across the intestinal wall into the blood) is attached to the "Layersomes".

Differences

In this case, insulin is directly delivered through pill.

In case of diabetes tablets,
Diabetes tablets work in different ways to lower blood glucose levels -
For example by stimulating the pancreas to produce more insulin, or by helping the body to use the insulin that it does produce more effectively"

Benefits
No need to use needles which is quite painful. Easy delivery. Easy to use.


P.S. Just an engineer who read Biology till 10 Class.

 

[kbd-raaf]

Buddy you can google all you want. I am only telling you and OP that this discovery has already been made and commercial oral insulin is available in market. Its you who have to prove that it is the discovery of an Indian scientist not me. Thanks

That's been proved.

Commercial Oral insulin has not been available. The Israeli company you linked (Oramed) is conducting trials, it is NOT commercially available

 

[Rajput_Pakistani]

@Rajput_Pakistani

Objective of Research ---- A way to transform delivery of insulin therapy

Challenge ---- From a shot to a pill. (Direct Delivery of Insulin)

Introduction

1. The body's digestive enzymes. ----
Extremely efficient in breaking down food.
It also break down insulin before it can get to work.

2. Insulin doesn't get easily absorbed through the gut into the bloodstream.

For Delivery Mechanism-

1. Packaging insulin in tiny sacs made of lipids, or fats called liposomes,(lready used in some treatments.)
2. Then, they wrapped the liposomes in layers of protective molecules called polyelectrolytes.

For Better Absorption into Bloodstream -
Folic acid, a kind of vitamin B ( helps in transporting liposomes across the intestinal wall into the blood) is attached to the "Layersomes".

Differences

In this case, insulin is directly delivered through pill.

In case of diabetes tablets,
Diabetes tablets work in different ways to lower blood glucose levels -
For example by stimulating the pancreas to produce more insulin, or by helping the body to use the insulin that it does produce more effectively"

Benefits
No need to use needles which is quite painful. Easy delivery. Easy to use.


P.S. Just an engineer who read Biology till 12 Class.

Sure you tell me everything regarding basics of Pharmacology. My questions still remains what is the innovation of Indians (as you are claiming that its a discovery)?

Oral Insulin is already available and it is discovered already.

That's been proved.

Commercial Oral insulin has not been available. The Israeli company you linked (Oramed) is conducting trials, it is NOT commercially available

Is the insulin (your countrymen discovered) is available commercially? Have you conducted its trials?
What is the new discovery you are claiming?

 

[KRAIT]

Sure you tell me everything regarding basics of Pharmacology. My questions still remains what is the innovation of Indians (as you are claiming that its a discovery)?Oral Insulin is already available and it is discovered already.
Is the insulin (your countrymen discovered) is available commercially? Have you conducted its trials?
What is the new discovery you are claiming?

Delivery and Absorption assistance mechanism.

 

[HariPrasad]

@Rajput_Pakistani

Objective of Research ---- A way to transform delivery of insulin therapy

Challenge ---- From a shot to a pill. (Direct Delivery of Insulin)

Introduction

1. The body's digestive enzymes. ----
Extremely efficient in breaking down food.
It also break down insulin before it can get to work.

2. Insulin doesn't get easily absorbed through the gut into the bloodstream.

For Delivery Mechanism-

1. Packaging insulin in tiny sacs made of lipids, or fats called liposomes,(lready used in some treatments.)
2. Then, they wrapped the liposomes in layers of protective molecules called polyelectrolytes.

For Better Absorption into Bloodstream -
Folic acid, a kind of vitamin B ( helps in transporting liposomes across the intestinal wall into the blood) is attached to the "Layersomes".

Differences

In this case, insulin is directly delivered through pill.

In case of diabetes tablets,
Diabetes tablets work in different ways to lower blood glucose levels -
For example by stimulating the pancreas to produce more insulin, or by helping the body to use the insulin that it does produce more effectively"

Benefits
No need to use needles which is quite painful. Easy delivery. Easy to use.


P.S. Just an engineer who read Biology till 12 Class.

Arey bhai tumane to uski Hawa nikaldi.

 

[Rajput_Pakistani]

@KRAIT

Further FYI

GlaxoSmithKline and Nobex Sign Worldwide License Agreement to... -- re> LONDON, and RESEARCH TRIANGLE PARK, N.C., May 22 /PRNewswire/ --

If its new mechanism to by pass "First Pass Effect" then you should rename the thread as "Innovative way to deliver Insulin Orally" rather then "discovery"

Being an Engineer i hope you are familiar with the difference between the 2 terms.

 

[Dash]

Mind Reader and Controller. I delayed your response by brain waves.

......Thullastu....