A Sikh ethnostate (khalistan) as a buffer state between India and Pakistan ?
Kashmiri separatism is still a real thing, nothing close to that exists in Punjab, zero.
Doubt much will change with the Biden administration at all wrt their India-Pak policy. Expect trade and military ties to keep growing between India and the US, if anything, because Biden is such a globalist and a strictly not 'America firster' like Trump, India possibly stands to gain, and gain quite a lot if Biden and the west in general continue their long term strategy of decoupling (in part) from China by diversifying their supply chain across SE Asia.
Trump wasn't that bad for Pakistan. Pretty even handed when dealing with India-Pak, had a good rapport with Modi but hosted IK too and got along and listened to the Pak perspective as well. Kept India out of the Afghan deal, stepped in and helped behind the scenes with last year's skirmish. Apart from stopping some aid, didn't do much damage to US-Pak ties.
Think Obama and Israel, and Israel not only have a lot of clout within the US, they're a much more important ally than India. Obama took it as far as any POTUS could with his rhetoric, calling out the "most right wing government ever" of Israel ever and made plenty of positive overtures to the muslim world but also could not stop the settlements, and also funded the Iron Dome and everything else like the snake that he was.
India is no Israel but Biden is Obama 2.0 policy wise, rhetoric wise.. we may hear something from his administration but don't expect India to be sanctioned or for ties to fray in any way.
End of the day, the whole Kashmir and India Pakistan situation just isn't going to figure at the top of any US administration's agenda.. barring a crisis and serious threat of nuclear conflict breaking out. Last year's skirmish.. nobody was seriously worried about nuclear war, the ongoing Ladakh/Galwan incident.. nobody is seriously worried about nuclear war.
MAD is keeping things under control in this part of the world.
The new admin will be mostly busy on their domestic front and internal culture war, and Iran and China abroad.